TRT: Methods, Benefits, And What To Expect

Testosterone Replacement Therapy (TRT) is designed for men experiencing low testosterone levels. This condition can arise due to ageing or other health factors, leading to symptoms such as fatigue, low libido, mood swings, and reduced muscle mass.

In Australia, there are various TRT methods available, each offering distinct benefits, considerations, and availability. This guide will provide a thorough exploration of TRT options, what to expect from each, and the potential non-medical alternatives. If you’re exploring TRT as a treatment, always consult with a healthcare professional to tailor the therapy to your needs.

Please note: the information below is intended purely for educational purposes, and our GP partners do not recommend (or in some cases prescribe) all of these treatments.

Medical TRT Options in Australia

If natural approaches aren’t enough (see examples later in this article), there are several medical TRT options available in Australia. Each method has its advantages, disadvantages, and varying frequency of administration. Below is a detailed breakdown of the different TRT methods used in Australia and abroad. If you are joining CactusMen as a patient, we recommend discussing these options with your GP to make sure any treatment protocol is a good fit:

1. Testosterone Gels and Creams

• How It Works: These topical treatments are applied to the skin, typically on the upper arms, shoulders, or thighs. The testosterone is absorbed through the skin and enters the bloodstream, delivering a steady dose.

• Benefits: Gels and creams offer an easy-to-use, non-invasive option for men who prefer daily treatment. It provides stable testosterone levels when applied consistently.

• Considerations: The primary concern is the risk of accidental transfer to others through skin contact. It’s important to cover the application site with clothing and wash hands thoroughly after applying. Some patients also find the daily routine less convenient than other methods.

• Availability in Australia: can be prescribed in Australia.

2. Testosterone Injections

• How It Works: Injections deliver testosterone intramuscularly, typically in the gluteal muscles. There are different types of injections based on the testosterone ester used, ranging from short-acting to long-acting formulations. These injections can be given weekly, biweekly, monthly, or every 10-12 weeks depending on the formulation and clinical advice.

• Benefits: Injections are one of the more effective methods for maintaining steady testosterone levels over time. 

• Considerations: Some men may experience hormone fluctuations between doses, leading to energy level changes. Additionally, injections can sometimes cause pain or irritation at the injection site.

• Availability in Australia: can be prescribed in Australia.

3. Testosterone Patches (Androderm)

• How It Works: Patches deliver testosterone through the skin continuously over 24 hours. They are applied to different areas of the body, typically on the abdomen, back, or upper arm, and must be replaced daily.

• Benefits: Patches offer a convenient option for men who prefer a once-a-day application. They provide stable testosterone levels throughout the day.

• Considerations: Skin irritation can occur if the patches are applied repeatedly to the same area. Rotating the site of application can help minimise this. Patches also need to be worn continuously, which may be uncomfortable for some men.

• Availability in Australia: patches are available with a prescription but are less commonly used.

4. Testosterone Pellets

• How It Works: Pellets are implanted under the skin in a minor surgical procedure. Once inserted, they release testosterone slowly over 3 to 6 months, eliminating the need for frequent dosing.

• Benefits: Pellets dissolve naturally and don’t need to be removed.

• Considerations: Since this method requires a surgical procedure, there’s a small risk of infection or pellet extrusion. It’s also more difficult to adjust the dosage once the pellets are implanted.

• Availability in Australia: Pellet therapy is less common in Australia. GPs partnering with CactusMen typically do not prescribe pellet-based therapy.

5. Oral Testosterone

• How It Works: Oral testosterone pills are taken by mouth and absorbed through the digestive system. This method is less common because it can cause elevated liver enzymes and potentially damage the liver over time.

• Benefits: Oral medication offers a simple and non-invasive option, but it’s not typically recommended due to health risks.

• Considerations: Oral testosterone is linked to an increased risk of liver damage and other side effects, which is why it is generally avoided.

• Availability in Australia: Oral therapy is not generally in Australia. GPs partnering with CactusMen do not prescribe pellet-based therapy.

Non-Medical Alternatives to TRT

Before considering medical testosterone replacement, some men may explore natural or lifestyle-based alternatives that could help boost testosterone levels. While these methods may offer some support, they are generally less effective than medical TRT. It’s essential to approach them with realistic expectations.

1. Exercise and Strength Training: Regular physical activity, particularly weight lifting and high-intensity interval training (HIIT), can help maintain healthy testosterone levels. Exercise has been shown to temporarily boost testosterone, but long-term benefits vary from person to person.

2. Diet: A diet rich in zinc, vitamin D, and healthy fats, such as those found in avocados and oily fish, can contribute to maintaining testosterone. Consuming a balanced diet with enough protein and carbs supports hormone health.

3. Supplements: While supplements like D-aspartic acid, fenugreek, and tribulus terrestris are marketed as testosterone boosters, their efficacy remains limited and unproven in clinical settings. Always consult a doctor before trying these options, as they may cause side effects or interact with other medications.

4. Sleep and Stress Reduction: Quality sleep is critical for testosterone production. Stress reduction techniques like meditation or mindfulness can also help maintain healthier testosterone levels, as chronic stress leads to elevated cortisol, which negatively affects testosterone.

Summary: While these non-medical approaches can support testosterone health, they should not replace proper medical advice or treatment for diagnosed testosterone deficiencies.

Is TRT Right for You? Key Considerations

Before starting TRT, it’s essential to understand that every man’s experience will be different, and the suitability of TRT depends on your specific health profile. TRT is not a “quick fix” for low energy or decreased libido; it’s a medical treatment designed to correct clinically low testosterone levels.

Common signs that you may benefit from TRT include:

• Persistent fatigue
• Low libido or erectile dysfunction
• Reduced muscle mass or strength
• Mood changes, including depression or irritability

Always consult a qualified healthcare professional to confirm if TRT is the right approach for you and to monitor any potential side effects or health risks.